Dat Q Tran Selected Research

rhesus-theta-defensin-1

1/2022	Preclinical Pharmacokinetics and Safety of Intravenous RTD-1.
12/2019	RTD-1 therapeutically normalizes synovial gene signatures in rat autoimmune arthritis and suppresses proinflammatory mediators in RA synovial fibroblasts.
11/2019	Rhesus Theta Defensin 1 Promotes Long Term Survival in Systemic Candidiasis by Host Directed Mechanisms.
1/2017	Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide.
1/2016	Rhesus θ-defensin-1 (RTD-1) exhibits in vitro and in vivo activity against cystic fibrosis strains of Pseudomonas aeruginosa.

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Dat Q Tran Research Topics

Disease

7	Inflammation (Inflammations) 01/2022 - 01/2012
7	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 05/2009
4	Infections 12/2021 - 09/2005
3	Necrotizing Enterocolitis 10/2018 - 07/2014
2	Arthritis (Polyarthritis) 12/2019 - 01/2017
2	Rheumatoid Arthritis 12/2019 - 01/2017
2	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2019 - 05/2009
2	Colic (Abdominal Cramps) 10/2018 - 02/2016
1	Severe Acute Respiratory Syndrome 01/2022
1	COVID-19 01/2022
1	Autoimmune Polyendocrinopathies (Schmidt Syndrome) 01/2022
1	X-Linked Syndrome Enteropathy Polyendocrinopathy Immune Dysregulation 01/2022
1	Acute Lung Injury 01/2022
1	Septic Shock (Toxic Shock Syndrome) 12/2021
1	Gram-Negative Bacterial Infections 12/2021
1	Sepsis (Septicemia) 12/2021
1	Mycoses (Diseases, Fungus) 10/2020
1	Systemic candidiasis 11/2019
1	Candidiasis (Moniliasis) 11/2019
1	Respiratory Tract Infections (Respiratory Tract Infection) 10/2018
1	Diarrhea 10/2018
1	Joint Diseases (Joint Disease) 01/2017
1	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2017
1	Cystic Fibrosis (Mucoviscidosis) 01/2016
1	Carcinogenesis 01/2013
1	Neoplasms (Cancer) 11/2010
1	Reinfection 09/2005

Drug/Important Bio-Agent (IBA)

6	CytokinesIBA 12/2021 - 01/2012
5	rhesus-theta-defensin-1IBA 01/2022 - 01/2016
3	Peptides (Polypeptides)IBA 12/2021 - 01/2016
3	DefensinsIBA 11/2019 - 01/2017
3	Anti-Bacterial Agents (Antibiotics)IBA 11/2019 - 09/2005
2	Transcription Factors (Transcription Factor)IBA 01/2022 - 01/2017
2	theta-defensinIBA 12/2021 - 11/2019
2	pristane (pristan)IBA 12/2019 - 01/2017
2	Leukocyte L1 Antigen Complex (Calgranulin)IBA 02/2016 - 01/2012
2	Biomarkers (Surrogate Marker)IBA 02/2016 - 07/2014
1	EndotoxinsIBA 01/2022
1	Carbapenems (Carbapenem Antibiotics)IBA 12/2021
1	EchinocandinsIBA 10/2020
1	PolyenesIBA 10/2020
1	AzolesIBA 10/2020
1	Antimicrobial Cationic PeptidesIBA 12/2019
1	Interleukin-6 (Interleukin 6)IBA 11/2019
1	Toll-Like Receptor 2IBA 01/2018
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018
1	Inosine FDA Link 01/2017
1	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 01/2017
1	L-SelectinIBA 02/2016
1	Interleukin-2 Receptors (IL 2 Receptor)IBA 01/2013
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2012
1	Interleukin-12 (IL 12)IBA 09/2005
1	Interferon-gamma (Interferon, gamma)IBA 09/2005

Therapy/Procedure

5	Therapeutics 01/2019 - 09/2005
3	Immunotherapy 01/2019 - 05/2009
1	Aftercare (After-Treatment) 02/2016